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Reversible S-glutathionylation of human 6-pyruvoyl tetrahydropterin synthase protects its enzymatic activity

6-Pyruvoyl tetrahydropterin synthase (PTS) converts 7,8-dihydroneopterin triphosphate into 6-pyruvoyltetrahydropterin and is a critical enzyme for the de novo synthesis of tetrahydrobiopterin, an essential cofactor for aromatic amino acid hydroxylases and nitric-oxide synthases. Neopterin derived fr...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Hara, Satoshi, Fukumura, Soichiro, Ichinose, Hiroshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349096/
https://ncbi.nlm.nih.gov/pubmed/30514762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005280
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