miRNA length variation during macrophage stimulation confounds the interpretation of results: implications for miRNA quantification by RT-qPCR

Most microRNAs (miRNAs) are expressed as a mix of length isoforms (referred to as isomiRs). IsomiR stoichiometry can be differentially impacted upon cell stimulation, as recently evidenced by our group in the context of immune responses induced by type-I interferon (IFN). Here, we revisit published...

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Udgivet i:RNA
Main Authors: Pillman, Katherine A., Goodall, Gregory J., Bracken, Cameron P., Gantier, Michael P.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348984/
https://ncbi.nlm.nih.gov/pubmed/30487268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.069047.118
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