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miRNA length variation during macrophage stimulation confounds the interpretation of results: implications for miRNA quantification by RT-qPCR

Most microRNAs (miRNAs) are expressed as a mix of length isoforms (referred to as isomiRs). IsomiR stoichiometry can be differentially impacted upon cell stimulation, as recently evidenced by our group in the context of immune responses induced by type-I interferon (IFN). Here, we revisit published...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Pillman, Katherine A., Goodall, Gregory J., Bracken, Cameron P., Gantier, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348984/
https://ncbi.nlm.nih.gov/pubmed/30487268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.069047.118
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