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Acquisition of T790M resistance mutation in a patient with advanced adenocarcinoma harbouring uncommon EGFR mutations: a case report and literature review

BACKGROUND: Osimertinib is the standard of care for patients with non-small-cell lung cancer (NSCLC) patients harboring acquired EGFR T790M resistance mutation. However, the frequency of T790M resistance mutation acquisition and the efficacy of osimertinib in patients harboring uncommon EGFR mutatio...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Hakozaki, Taiki, Yomota, Makiko
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348971/
https://ncbi.nlm.nih.gov/pubmed/30774361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S190034
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