Case Report: Germline Mutation of T790M and Dual/Multiple EGFR Mutations in Patients with Lung Adenocarcinoma

INTRODUCTION: The epidermal growth factor receptor (EGFR) T790M mutation remains one of the major mechanisms of resistance to EGFR tyrosine kinase inhibitors (TKI) treatment. Cases of de novo EGFR T790M mutations prior to TKI treatment have been reported, but most of them were somatic mutations. In...

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Publicado no:Clin Lung Cancer
Main Authors: Lou, Yanyan, Pecot, Chad V., Tran, Hai T., DeVito, Vikki J., Tang, Xi Ming, Heymach, John, Luthra, Raja, Wistuba, Ignacio I., Zuo, Zhuang, Tsao, Anne S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119523/
https://ncbi.nlm.nih.gov/pubmed/26700910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cllc.2015.11.003
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