Removal of Microglial-Specific MyD88 Signaling Alters Dentate Gyrus Doublecortin and Enhances Opioid Addiction-like Behaviors

Drugs of abuse promote a potent immune response in central nervous system (CNS) via the activation of microglia and astrocytes. However, the molecular mechanisms underlying microglial activation during addiction are not well known. We developed and functionally characterized a novel transgenic mouse...

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Vydáno v:Brain Behav Immun
Hlavní autoři: Rivera, Phillip D., Hanamsagar, Richa, Kan, Matthew J., Tran, Phuong K, Stewart, David, Jo, Young Chan, Gunn, Michael, Bilbo, Staci D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348129/
https://ncbi.nlm.nih.gov/pubmed/30447281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2018.11.010
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