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Removal of Microglial-Specific MyD88 Signaling Alters Dentate Gyrus Doublecortin and Enhances Opioid Addiction-like Behaviors

Drugs of abuse promote a potent immune response in central nervous system (CNS) via the activation of microglia and astrocytes. However, the molecular mechanisms underlying microglial activation during addiction are not well known. We developed and functionally characterized a novel transgenic mouse...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Brain Behav Immun
Κύριοι συγγραφείς: Rivera, Phillip D., Hanamsagar, Richa, Kan, Matthew J., Tran, Phuong K, Stewart, David, Jo, Young Chan, Gunn, Michael, Bilbo, Staci D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348129/
https://ncbi.nlm.nih.gov/pubmed/30447281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2018.11.010
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