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Engineering Saccharomyces cerevisiae for production of simvastatin

Simvastatin is a semisynthetic cholesterol-lowering medication and one of the top-selling statins in the world. Currently, industrial production of simvastatin acid (SVA) is a multistep process starting from the natural product lovastatin. For this reason, there is significant interest in direct pro...

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書目詳細資料
發表在:Metab Eng
Main Authors: Bond, Carly M., Tang, Yi
格式: Artigo
語言:Inglês
出版: 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348118/
https://ncbi.nlm.nih.gov/pubmed/30213650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2018.09.005
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