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Engineering Saccharomyces cerevisiae for production of simvastatin

Simvastatin is a semisynthetic cholesterol-lowering medication and one of the top-selling statins in the world. Currently, industrial production of simvastatin acid (SVA) is a multistep process starting from the natural product lovastatin. For this reason, there is significant interest in direct pro...

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Bibliografische gegevens
Gepubliceerd in:Metab Eng
Hoofdauteurs: Bond, Carly M., Tang, Yi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348118/
https://ncbi.nlm.nih.gov/pubmed/30213650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2018.09.005
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