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Engineering Saccharomyces cerevisiae for production of simvastatin
Simvastatin is a semisynthetic cholesterol-lowering medication and one of the top-selling statins in the world. Currently, industrial production of simvastatin acid (SVA) is a multistep process starting from the natural product lovastatin. For this reason, there is significant interest in direct pro...
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| Publicado no: | Metab Eng |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6348118/ https://ncbi.nlm.nih.gov/pubmed/30213650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2018.09.005 |
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