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Atherosclerosis-associated differentially methylated regions can reflect the disease phenotype and are often at enhancers

BACKGROUND AND AIMS: Atherosclerosis is a widespread and complicated disease involving phenotypic modulation and transdifferentiation of vascular smooth muscle cells (SMCs), the predominant cells in aorta, as well as changes in endothelial cells and infiltrating monocytes. Alterations in DNA methyla...

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Detalhes bibliográficos
Publicado no:Atherosclerosis
Main Authors: Lacey, Michelle, Baribault, Carl, Ehrlich, Kenneth C., Ehrlich, Melanie
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348116/
https://ncbi.nlm.nih.gov/pubmed/30529831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2018.11.031
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