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Atherosclerosis-associated differentially methylated regions can reflect the disease phenotype and are often at enhancers

BACKGROUND AND AIMS: Atherosclerosis is a widespread and complicated disease involving phenotypic modulation and transdifferentiation of vascular smooth muscle cells (SMCs), the predominant cells in aorta, as well as changes in endothelial cells and infiltrating monocytes. Alterations in DNA methyla...

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Publicat a:Atherosclerosis
Autors principals: Lacey, Michelle, Baribault, Carl, Ehrlich, Kenneth C., Ehrlich, Melanie
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348116/
https://ncbi.nlm.nih.gov/pubmed/30529831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2018.11.031
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