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Holographic Characterization of Protein Aggregates in the Presence of Silicone Oil and Surfactants

Characterizing protein aggregates in the presence of silicone oil is a long standing challenge for the pharmaceutical industry. Silicone oil is often used as a lubricant in devices that deliver and store therapeutic protein products, and has been linked to protein aggregation, which can compromise a...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Kasimbeg, Priya N. O., Cheong, Fook Chiong, Ruffner, David B., Blusewicz, Jaroslaw M., Philips, Laura A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348100/
https://ncbi.nlm.nih.gov/pubmed/30315809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2018.10.002
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