Levetiracetam optimal dose-finding as first-line treatment for neonatal seizures occurring in the context of hypoxic-ischaemic encephalopathy (LEVNEONAT-1): study protocol of a phase II trial

INTRODUCTION: Therapeutic schedules for treating neonatal seizures remain elusive. First-line treatment with phenobarbital is widely supported but without strong scientific evidence. Levetiracetam (LEV) is an emerging and promising antiepileptic drug (AED). The aim of this phase II trial is to deter...

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Xehetasun bibliografikoak
Argitaratua izan da:BMJ Open
Egile Nagusiak: Favrais, Geraldine, Ursino, Moreno, Mouchel, Catherine, Boivin, Estelle, Jullien, Vincent, Zohar, Sarah, Saliba, Elie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMJ Publishing Group 2019
Gaiak:
Paediatrics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347888/
https://ncbi.nlm.nih.gov/pubmed/30679288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-022739
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