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Levetiracetam optimal dose-finding as first-line treatment for neonatal seizures occurring in the context of hypoxic-ischaemic encephalopathy (LEVNEONAT-1): study protocol of a phase II trial

INTRODUCTION: Therapeutic schedules for treating neonatal seizures remain elusive. First-line treatment with phenobarbital is widely supported but without strong scientific evidence. Levetiracetam (LEV) is an emerging and promising antiepileptic drug (AED). The aim of this phase II trial is to deter...

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Bibliografiske detaljer
Udgivet i:BMJ Open
Main Authors: Favrais, Geraldine, Ursino, Moreno, Mouchel, Catherine, Boivin, Estelle, Jullien, Vincent, Zohar, Sarah, Saliba, Elie
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347888/
https://ncbi.nlm.nih.gov/pubmed/30679288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-022739
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