Antagonistic paralogs control a switch between growth and pathogen resistance in C. elegans

Immune genes are under intense, pathogen-induced pressure, which causes these genes to diversify over evolutionary time and become species-specific. Through a forward genetic screen we recently described a C. elegans-specific gene called pals-22 to be a repressor of “Intracellular Pathogen Response”...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Reddy, Kirthi C., Dror, Tal, Underwood, Ryan S., Osman, Guled A., Elder, Corrina R., Desjardins, Christopher A., Cuomo, Christina A., Barkoulas, Michalis, Troemel, Emily R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347328/
https://ncbi.nlm.nih.gov/pubmed/30640956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007528
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