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An intracellular pathogen response pathway promotes proteostasis in C. elegans

Maintenance of protein homeostasis, or proteostasis, is crucial for organismal health. Disruption of proteostasis can lead to the accumulation of protein aggregates, which are associated with aging and many human diseases such as Alzheimer’s disease [1–3]. Through analysis of the C. elegans host res...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Reddy, Kirthi C., Dror, Tal, Sowa, Jessica N., Panek, Johan, Chen, Kevin, Lim, Efrem S., Wang, David, Troemel, Emily R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698132/
https://ncbi.nlm.nih.gov/pubmed/29103937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.10.009
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