Mitochondria-targeted cyclosporin A delivery system to treat myocardial ischemia reperfusion injury of rats

BACKGROUND: Cyclosporin A (CsA) is a promising therapeutic drug for myocardial ischemia reperfusion injury (MI/RI) because of its definite inhibition to the opening of mitochondrial permeability transition pore (mPTP). However, the application of cyclosporin A to treat MI/RI is limited due to its im...

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Dettagli Bibliografici
Pubblicato in:J Nanobiotechnology
Autori principali: Zhang, Chang-xiong, Cheng, Ying, Liu, Dao-zhou, Liu, Miao, Cui, Han, Zhang, Bang-le, Mei, Qi-bing, Zhou, Si-yuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346555/
https://ncbi.nlm.nih.gov/pubmed/30683110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0451-9
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