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Profiling the Photochemical-Induced Degradation of Rat Growth Hormone with Extreme Ultra-pressure Chromatography-Mass Spectrometry Utilizing Meter-Long Microcapillary Columns Packed with Sub-2-μm Particles

In recent years protein therapeutics have seen increasing use in the therapeutic arena. As with traditional small molecule drug substances, one is obligated to ensure purity and stability of the various dosage forms. With these higher molecular weight therapeutics a common approach for analytical ch...

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Detalhes bibliográficos
Publicado no:Chromatographia
Main Authors: Mozziconacci, Olivier, Stobaugh, Jordan T., Bommana, Rupesh, Woods, Joshua, Franklin, Edward, Jorgenson, James W., Forrest, M. Laird, Schöneich, Christian, Stobaugh, John F
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346430/
https://ncbi.nlm.nih.gov/pubmed/30686829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10337-017-3344-9
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