Clustering, Spatial Distribution and Phosphorylation of Discoidin Domain Receptors 1 and 2 in Response to Soluble Collagen Type I

Discoidin Domain Receptors (DDR1 and DDR2) are receptor tyrosine kinases that signal in response to collagen. We had previously shown that collagen binding leads to clustering of DDR1b, a process partly mediated by its extracellular domain (ECD). In this study, we investigated (i) the impact of the...

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Publicat a:J Mol Biol
Autors principals: Yeung, David A., Shanker, Nirvan, Sohail, Anjum, Weiss, Brent A., Wang, Carolyn, Wellmerling, Jack, Das, Subhadip, Ganju, Ramesh K., Miller, Jeanette L. C., Herr, Andrew B., Fridman, Rafael, Agarwal, Gunjan
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346271/
https://ncbi.nlm.nih.gov/pubmed/30458172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.11.015
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