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Polygenic Score for Alzheimer Disease and Cognition: The Mediating Role of Personality

Alzheimer’s disease (AD) polygenic risk score (PGS) is associated with lower cognitive functioning even among older individuals without dementia. We tested the hypothesis that personality traits mediate the association between AD genetic risk and cognitive functioning. Participants (N >7,000, age...

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Bibliografiske detaljer
Udgivet i:J Psychiatr Res
Main Authors: Stephan, Yannick, Sutin, Angelina R., Luchetti, Martina, Caille, Pauline, Terracciano, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346269/
https://ncbi.nlm.nih.gov/pubmed/30384091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpsychires.2018.10.015
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