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Polygenic Score for Alzheimer Disease and Cognition: The Mediating Role of Personality

Alzheimer’s disease (AD) polygenic risk score (PGS) is associated with lower cognitive functioning even among older individuals without dementia. We tested the hypothesis that personality traits mediate the association between AD genetic risk and cognitive functioning. Participants (N >7,000, age...

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Detalhes bibliográficos
Publicado no:J Psychiatr Res
Main Authors: Stephan, Yannick, Sutin, Angelina R., Luchetti, Martina, Caille, Pauline, Terracciano, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346269/
https://ncbi.nlm.nih.gov/pubmed/30384091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpsychires.2018.10.015
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