CCNG1 (Cyclin G1) regulation by mutant‐P53 via induction of Notch3 expression promotes high‐grade serous ovarian cancer (HGSOC) tumorigenesis and progression

TP53 mutation is considerably common in advanced high‐grade serous ovarian cancer (HGSOC) and significantly associated with a poor prognosis. In this study, we investigated the role of Cyclin G1 (CCNG1), a target gene of wild‐type TP53 (P53wt), in HGSOC and the possible regulatory mechanism between...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Xu, Ying, Zhang, Qing, Miao, Chunying, Dongol, Samina, Li, Yinuo, Jin, Chenjuan, Dong, Ruifeng, Li, Yingwei, Yang, Xingsheng, Kong, Beihua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346265/
https://ncbi.nlm.nih.gov/pubmed/30565428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1812
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