CCNG1 (Cyclin G1) regulation by mutant‐P53 via induction of Notch3 expression promotes high‐grade serous ovarian cancer (HGSOC) tumorigenesis and progression

TP53 mutation is considerably common in advanced high‐grade serous ovarian cancer (HGSOC) and significantly associated with a poor prognosis. In this study, we investigated the role of Cyclin G1 (CCNG1), a target gene of wild‐type TP53 (P53wt), in HGSOC and the possible regulatory mechanism between...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancer Med
Hauptverfasser: Xu, Ying, Zhang, Qing, Miao, Chunying, Dongol, Samina, Li, Yinuo, Jin, Chenjuan, Dong, Ruifeng, Li, Yingwei, Yang, Xingsheng, Kong, Beihua
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Cancer Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346265/
https://ncbi.nlm.nih.gov/pubmed/30565428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1812
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge