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Mycobacterium tuberculosis Requires Regulation of ESX-5 Secretion for Virulence in Irgm1-Deficient Mice

The Mycobacterium tuberculosis type VII secretion system ESX-5, which has been implicated in virulence, is activated at the transcriptional level by the phosphate starvation-responsive Pst/SenX3-RegX3 signal transduction system. Deletion of pstA1, which encodes a Pst phosphate transporter component,...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Elliott, Sarah R., White, Dylan W., Tischler, Anna D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346127/
https://ncbi.nlm.nih.gov/pubmed/30455198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00660-18
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