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Phosphate Starvation: a Novel Signal that Triggers ESX-5 Secretion in Mycobacterium tuberculosis

Mycobacterium tuberculosis uses the Type VII ESX secretion systems to transport proteins across its complex cell wall. ESX-5 has been implicated in M. tuberculosis virulence, but the regulatory mechanisms controlling ESX-5 secretion were unknown. Here we uncover a link between ESX-5 and the Pst/SenX...

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Publicado en:Mol Microbiol
Main Authors: Elliott, Sarah R., Tischler, Anna D.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863468/
https://ncbi.nlm.nih.gov/pubmed/26800324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13332
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