Mammalian plasma fetuin-B is a selective inhibitor of ovastacin and meprin metalloproteinases

Vertebrate fetuins are multi-domain plasma-proteins of the cystatin-superfamily. Human fetuin-A is also known as AHSG, α(2)-Heremans-Schmid-glycoprotein. Gene-knockout in mice identified fetuin-A as essential for calcified-matrix-metabolism and bone-mineralization. Fetuin-B deficient mice, on the ot...

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Publicat a:Sci Rep
Autors principals: Karmilin, Konstantin, Schmitz, Carlo, Kuske, Michael, Körschgen, Hagen, Olf, Mario, Meyer, Katharina, Hildebrand, André, Felten, Matthias, Fridrich, Sven, Yiallouros, Irene, Becker-Pauly, Christoph, Weiskirchen, Ralf, Jahnen-Dechent, Willi, Floehr, Julia, Stöcker, Walter
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346019/
https://ncbi.nlm.nih.gov/pubmed/30679641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37024-5
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