Intracellular activation of ovastacin mediates pre-fertilization hardening of the zona pellucida

STUDY QUESTION: How and where is pro-ovastacin activated and how does active ovastacin regulate zona pellucida hardening (ZPH) and successful fertilization? STUDY FINDING: Ovastacin is partially active before exocytosis and pre-hardens the zona pellucida (ZP) before fertilization. WHAT IS KNOWN ALRE...

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Detalhes bibliográficos
Publicado no:Mol Hum Reprod
Main Authors: Körschgen, Hagen, Kuske, Michael, Karmilin, Konstantin, Yiallouros, Irene, Balbach, Melanie, Floehr, Julia, Wachten, Dagmar, Jahnen-Dechent, Willi, Stöcker, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909858/
https://ncbi.nlm.nih.gov/pubmed/28911209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gax040
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