Application of the Transcriptional Disease Signature (TDSs) to Screen Melanoma-Effective Compounds in a Small Fish Model

Cell culture and protein target-based compound screening strategies, though broadly utilized in selecting candidate compounds, often fail to eliminate candidate compounds with non-target effects and/or safety concerns until late in the drug developmental process. Phenotype screening using intact res...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lu, Yuan, Boswell, William, Boswell, Mikki, Klotz, Barbara, Kneitz, Susanne, Regneri, Janine, Savage, Markita, Mendoza, Cristina, Postlethwait, John, Warren, Wesley C., Schartl, Manfred, Walter, Ronald B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345854/
https://ncbi.nlm.nih.gov/pubmed/30679619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36656-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados