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STAT3 is activated in multicellular spheroids of colon carcinoma cells and mediates expression of IRF9 and interferon stimulated genes

Three-dimensional cell cultures, such as multicellular spheroids (MCS), reflect the in vivo architecture of solid tumours and multicellular drug resistance. We previously identified interferon regulatory factor 9 (IRF9) to be responsible for the up-regulation of a subset of interferon (IFN)-stimulat...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Edsbäcker, Elin, Serviss, Jason T., Kolosenko, Iryna, Palm-Apergi, Caroline, De Milito, Angelo, Tamm, Katja Pokrovskaja
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345781/
https://ncbi.nlm.nih.gov/pubmed/30679726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37294-z
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