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A Combined Targeted and Whole Exome Sequencing Approach Identified Novel Candidate Genes Involved in Heritable Pulmonary Arterial Hypertension

The pathogenesis of idiopathic and heritable forms of pulmonary arterial hypertension is still not completely understood, even though several causative genes have been proposed, so that a third of patients remains genetically unresolved. Here we applied a multistep approach to extend identification...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Barozzi, Chiara, Galletti, Margherita, Tomasi, Luciana, De Fanti, Sara, Palazzini, Massimiliano, Manes, Alessandra, Sazzini, Marco, Galiè, Nazzareno
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345742/
https://ncbi.nlm.nih.gov/pubmed/30679663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37277-0
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