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A Combined Targeted and Whole Exome Sequencing Approach Identified Novel Candidate Genes Involved in Heritable Pulmonary Arterial Hypertension

The pathogenesis of idiopathic and heritable forms of pulmonary arterial hypertension is still not completely understood, even though several causative genes have been proposed, so that a third of patients remains genetically unresolved. Here we applied a multistep approach to extend identification...

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Publicado en:Sci Rep
Main Authors: Barozzi, Chiara, Galletti, Margherita, Tomasi, Luciana, De Fanti, Sara, Palazzini, Massimiliano, Manes, Alessandra, Sazzini, Marco, Galiè, Nazzareno
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345742/
https://ncbi.nlm.nih.gov/pubmed/30679663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37277-0
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