Impaired Cu–Zn Superoxide Dismutase (SOD1) and Calcineurin (Cn) Interaction in ALS: A Presumed Consequence for TDP-43 and Zinc Aggregation in Tg SOD1(G93A) Rodent Spinal Cord Tissue

Impaired interactions between Calcineurin (Cn) and (Cu/Zn) superoxide dismutase (SOD1) are suspected to be responsible for the formation of hyperphosphorylated protein aggregation in amyotrophic lateral sclerosis (ALS). Serine (Ser)- enriched phosphorylated TDP-43 protein aggregation appears in the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurochem Res
Prif Awduron: Kim, Jolene M., Billington, Elizabeth, Reyes, Ada, Notarianni, Tara, Sage, Jessica, Agbas, Emre, Taylor, Michael, Monast, Ian, Stanford, John A., Agbas, Abdulbaki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2018
Pynciau:
Original Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345727/
https://ncbi.nlm.nih.gov/pubmed/29299811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-017-2461-z
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg