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TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial–mesenchymal transition and metastasis in liver cancer

Metastasis is the main cause of cancer mortality. However, the triggering mechanisms and regulation of epithelial–mesenchymal transition (EMT) factors in the commitment of metastasis have not been well characterized. Spermatogenic Zip 1 (SPZ1) acts as a proto-oncogene and an upstream regulator of EM...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Wang, Li-Ting, Wang, Shen-Nien, Chiou, Shyh-Shin, Liu, Kwei-Yan, Chai, Chee-Yin, Chiang, Cheng-Ming, Huang, Shau-Ku, Yokoyama, Kazunari K., Hsu, Shih-Hsien
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345675/
https://ncbi.nlm.nih.gov/pubmed/30154425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0457-z
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