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Transcription factor SPZ1 promotes TWIST-mediated epithelial–mesenchymal transition and oncogenesis in human liver cancer

The epithelial–mesenchymal transition (EMT) is an important process in the progression of cancer. However, its occurrence and mechanism of regulation are not fully understood. We propose a regulatory pathway in which spermatogenic leucine zipper 1 (SPZ1) promotes EMT through its transactivating abil...

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Publicat a:Oncogene
Autors principals: Wang, L-T, Chiou, S-S, Chai, C-Y, Hsi, E, Chiang, C-M, Huang, S-K, Wang, S-N, Yokoyama, K K, Hsu, S-H
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543259/
https://ncbi.nlm.nih.gov/pubmed/28368406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.69
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