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Filopodome Mapping Identifies p130Cas as a Mechanosensitive Regulator of Filopodia Stability

Filopodia are adhesive cellular protrusions specialized in the detection of extracellular matrix (ECM)-derived cues. Although ECM engagement at focal adhesions is known to trigger the recruitment of hundreds of proteins (“adhesome”) to fine-tune cellular behavior, the components of the filopodia adh...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Biol
Hauptverfasser: Jacquemet, Guillaume, Stubb, Aki, Saup, Rafael, Miihkinen, Mitro, Kremneva, Elena, Hamidi, Hellyeh, Ivaska, Johanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345628/
https://ncbi.nlm.nih.gov/pubmed/30639111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2018.11.053
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