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Cis-activation in the Notch signaling pathway

The Notch signaling pathway consists of transmembrane ligands and receptors that can interact both within the same cell (cis) and across cell boundaries (trans). Previous work has shown that cis-interactions act to inhibit productive signaling. Here, by analyzing Notch activation in single cells whi...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Nandagopal, Nagarajan, Santat, Leah A, Elowitz, Michael B
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345567/
https://ncbi.nlm.nih.gov/pubmed/30628888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37880
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