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Distinct Methylation Profiles Characterize Fusion-Positive and Fusion-Negative Rhabdomyosarcoma
Rhabdomyosarcoma comprises two major subtypes, fusion-positive (PAX3-FOXO1 or PAX7-FOXO1) and fusion-negative. To investigate the significance of DNA methylation in these subtypes, we analyzed methylation profiles of 37 rhabdomyosarcoma tumors and 10 rhabdomyosarcoma cell lines as well as 8 normal t...
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| Publicat a: | Mod Pathol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6345526/ https://ncbi.nlm.nih.gov/pubmed/26226845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2015.82 |
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