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Stop fRETting the Target: Next-Generation RET Inhibitors Have Arrived

BLU-667 is a next-generation RET inhibitor that maximizes on-target and minimizes off-target effects. It is an exemplar of genotype-driven drug development followed by multi-histology basket trial validation that is becoming a paradigm for precision oncology. Cancer Discov; 8(7); 797–9. ©2018 AACR....

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Bibliografische gegevens
Gepubliceerd in:Cancer Discov
Hoofdauteurs: lams, Wade T., Lovly, Christine M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345252/
https://ncbi.nlm.nih.gov/pubmed/29967074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-0489
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