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l-2-Oxothiazolidine-4-carboxylate reverses glutathione oxidation and delays fatigue of skeletal muscle in vitro

Fatiguing exercise promotes oxidation of intracellular thiols, notably glutathione. Interventions that oppose or reverse thiol oxidation can inhibit fatigue. The reduced cysteine donor l-2-oxothiazolidine-4-carboxylate (OTC) supports glutathione synthesis and is approved for use in humans but has no...

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Vydáno v:J Appl Physiol (1985)
Hlavní autoři: Ferreira, Leonardo F., Gilliam, Laura A. A., Reid, Michael B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345207/
https://ncbi.nlm.nih.gov/pubmed/19407260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00001.2009
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