Intravital imaging reveals systemic ezrin inhibition impedes cancer cell migration and lymph node metastasis in breast cancer

BACKGROUND: Limited understanding of the cancer biology of metastatic sites is a major factor contributing to poor outcomes in cancer patients. The regional lymph nodes are the most common site of metastasis in most solid cancers and their involvement is a strong predictor of relapse in breast cance...

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Publicado en:Breast Cancer Res
Autores principales: Ghaffari, Abdi, Hoskin, Victoria, Turashvili, Gulisa, Varma, Sonal, Mewburn, Jeff, Mullins, Graeme, Greer, Peter A., Kiefer, Friedemann, Day, Andrew G., Madarnas, Yolanda, SenGupta, Sandip, Elliott, Bruce E.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345049/
https://ncbi.nlm.nih.gov/pubmed/30678714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-1079-7
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