The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer

BACKGROUND: The role of tumor protein D54 in breast cancer has not been studied and its function in breast cancer remains unclear. In our previous pharmacogenomic studies using lymphoblastoid cell line (LCL), this protein has been identified to affect metformin response. Although metformin has been...

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Vydáno v:Cancer Metab
Hlavní autoři: Zhuang, Yongxian, Ly, Reynold C., Frazier, Carleigh V., Yu, Jia, Qin, Sisi, Fan, Xiao-Yang, Goetz, Matthew P., Boughey, Judy C., Weinshilboum, Richard, Wang, Liewei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345044/
https://ncbi.nlm.nih.gov/pubmed/30697423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-018-0193-4
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