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Sox7 negatively regulates prostate-specific membrane antigen (PSMA) expression through PSMA-enhancer

BACKGROUND. PSMA expression in the prostate epithelium is controlled by a cis-element, PSMA enhancer (PSME). PSME contains multiple binding sites for Sox proteins, and in this study, we identified Sox7 protein as a negative regulator of PSMA expression through its interaction with PSME. METHODS. The...

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Detalhes bibliográficos
Publicado no:Prostate
Main Authors: Peng, Wei, Guo, Lizheng, Tang, Ruoyi, Liu, Xiuju, Jin, Rui, Dong, Jin-Tang, Xing, Chun-gen, Zhou, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344945/
https://ncbi.nlm.nih.gov/pubmed/30488457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23743
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