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Synthesis and evaluation of [(64)Cu]PSMA-617 targeted for prostate-specific membrane antigen in prostate cancer

We radiolabeled a ligand, PSMA-617, of prostate-specific membrane antigen (PSMA) with copper-64 ((64)Cu), to evaluate the metabolism, biodistribution, and potential of [(64)Cu]PSMA-617 for PET imaging of prostate cancer. [(64)Cu]PSMA-617 was synthesized by heating PSMA-617 with [(64)Cu]CuCl(2) in bu...

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Bibliographic Details
Published in:Am J Nucl Med Mol Imaging
Main Authors: Cui, Can, Hanyu, Masayuki, Hatori, Akiko, Zhang, Yiding, Xie, Lin, Ohya, Tomoya, Fukada, Masami, Suzuki, Hisashi, Nagatsu, Kotaro, Jiang, Cuiping, Luo, Rui, Shao, Guoqiang, Zhang, Mingrong, Wang, Feng
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435610/
https://ncbi.nlm.nih.gov/pubmed/28533936
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