Detection of influenza A(H3N2) viruses exhibiting reduced susceptibility to the novel cap-dependent endonuclease inhibitor baloxavir in Japan, December 2018

The novel cap-dependent endonuclease inhibitor baloxavir marboxil was approved for the treatment of influenza virus infection in Japan in February 2018. Two influenza A(H3N2) viruses carrying an I38T substitution in the polymerase acidic subunit (PA) were detected in baloxavir-treated children in De...

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Detalhes bibliográficos
Publicado no:Euro Surveill
Main Authors: Takashita, Emi, Kawakami, Chiharu, Morita, Hiroko, Ogawa, Rie, Fujisaki, Seiichiro, Shirakura, Masayuki, Miura, Hideka, Nakamura, Kazuya, Kishida, Noriko, Kuwahara, Tomoko, Mitamura, Keiko, Abe, Takashi, Ichikawa, Masataka, Yamazaki, Masahiko, Watanabe, Shinji, Odagiri, Takato
Formato: Artigo
Idioma:Inglês
Publicado em: European Centre for Disease Prevention and Control (ECDC) 2019
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344841/
https://ncbi.nlm.nih.gov/pubmed/30670142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2807/1560-7917.ES.2019.24.3.1800698
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