Safety and effectiveness of eculizumab for pediatric patients with atypical hemolytic–uremic syndrome in Japan: interim analysis of post-marketing surveillance

BACKGROUND: In 2013, eculizumab was approved for treatment of the atypical hemolytic–uremic syndrome (aHUS) in Japan, which was defined as a thrombotic microangiopathy (TMA) excluding Shiga toxin-producing Escherichia coli-HUS and thrombotic thrombocytopenic purpura. Simultaneously, post-marketing s...

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Vydáno v:Clin Exp Nephrol
Hlavní autoři: Ito, Shuichi, Hidaka, Yoshihiko, Inoue, Norimitsu, Kaname, Shinya, Kato, Hideki, Matsumoto, Masanori, Miyakawa, Yoshitaka, Mizuno, Masashi, Okada, Hirokazu, Shimono, Akihiko, Matsuda, Takahisa, Maruyama, Shoichi, Fujimura, Yoshihiro, Nangaku, Masaomi, Kagami, Shoji
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Singapore 2018
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344608/
https://ncbi.nlm.nih.gov/pubmed/30039480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10157-018-1610-2
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