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Hypercapnia Alters Alveolar Epithelial Repair by a pH-Dependent and Adenylate Cyclase-Mediated Mechanism

Lung cell injury and repair is a hallmark of the acute respiratory distress syndrome (ARDS). Lung protective mechanical ventilation strategies in these patients may lead to hypercapnia (HC). Although HC has been explored in the clinical context of ARDS, its effect upon alveolar epithelial cell (AEC)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cortes-Puentes, Gustavo A., Westerly, Blair, Schiavo, Dante, Wang, Shaohua, Stroetz, Randolph, Walters, Bruce, Hubmayr, Rolf D., Oeckler, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344503/
https://ncbi.nlm.nih.gov/pubmed/30674971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36951-7
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