Hypercapnia Alters Alveolar Epithelial Repair by a pH-Dependent and Adenylate Cyclase-Mediated Mechanism

Lung cell injury and repair is a hallmark of the acute respiratory distress syndrome (ARDS). Lung protective mechanical ventilation strategies in these patients may lead to hypercapnia (HC). Although HC has been explored in the clinical context of ARDS, its effect upon alveolar epithelial cell (AEC)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Cortes-Puentes, Gustavo A., Westerly, Blair, Schiavo, Dante, Wang, Shaohua, Stroetz, Randolph, Walters, Bruce, Hubmayr, Rolf D., Oeckler, Richard A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344503/
https://ncbi.nlm.nih.gov/pubmed/30674971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36951-7
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