Clinical Utilization Pattern of Liquid Biopsies (LB) to Detect Actionable Driver Mutations, Guide Treatment Decisions and Monitor Disease Burden During Treatment of 33 Metastatic Colorectal Cancer (mCRC) Patients (pts) at a Fox Chase Cancer Center GI Oncology Subspecialty Clinic

Background: Liquid biopsy (LB) captures dynamic genomic alterations (alts) across metastatic colorectal cancer (mCRC) therapy and may complement tissue biopsy (TB). We sought to describe the utility of LB and better understand mCRC biology during therapy. Methods: Thirty-three patients (pts) with mC...

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Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: Ghatalia, Pooja, Smith, Chad H., Winer, Arthur, Gou, Jiangtao, Kiedrowski, Lesli A., Slifker, Michael, Saltzberg, Patricia D., Bubes, Nicole, Anari, Fern M., Kasireddy, Vineela, Varshavsky, Asya, Liu, Yang, Ross, Eric A., El-Deiry, Wafik S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344461/
https://ncbi.nlm.nih.gov/pubmed/30705875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00652
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