Clinical Utilization Pattern of Liquid Biopsies (LB) to Detect Actionable Driver Mutations, Guide Treatment Decisions and Monitor Disease Burden During Treatment of 33 Metastatic Colorectal Cancer (mCRC) Patients (pts) at a Fox Chase Cancer Center GI Oncology Subspecialty Clinic

Background: Liquid biopsy (LB) captures dynamic genomic alterations (alts) across metastatic colorectal cancer (mCRC) therapy and may complement tissue biopsy (TB). We sought to describe the utility of LB and better understand mCRC biology during therapy. Methods: Thirty-three patients (pts) with mC...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Ghatalia, Pooja, Smith, Chad H., Winer, Arthur, Gou, Jiangtao, Kiedrowski, Lesli A., Slifker, Michael, Saltzberg, Patricia D., Bubes, Nicole, Anari, Fern M., Kasireddy, Vineela, Varshavsky, Asya, Liu, Yang, Ross, Eric A., El-Deiry, Wafik S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344461/
https://ncbi.nlm.nih.gov/pubmed/30705875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00652
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