The Neuroprotector Benzothiazepine CGP37157 Extends Lifespan in C. elegans Worms

The benzothiazepine CGP37157 has shown neuroprotective effects in several in vitro models of excitotoxicity involving dysregulation of intracellular Ca(2+) homeostasis. Although its mechanism of neuroprotection is unclear, it is probably related with some of its effects on Ca(2+) homeostasis. CGP371...

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Detalles Bibliográficos
Publicado en:Front Aging Neurosci
Autores principales: García-Casas, Paloma, Arias-del-Val, Jessica, Alvarez-Illera, Pilar, Wojnicz, Aneta, de los Ríos, Cristobal, Fonteriz, Rosalba I., Montero, Mayte, Alvarez, Javier
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344432/
https://ncbi.nlm.nih.gov/pubmed/30705628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00440
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