Reduced GluN1 in mouse dentate gyrus is associated with CA3 hyperactivity and psychosis-like behaviors

Recent findings from in vivo-imaging and human post-mortem tissue studies in schizophrenic psychosis (SzP), have demonstrated functional and molecular changes in hippocampal subfields that can be associated with hippocampal hyperexcitability. In this study, we used a subfield-specific GluN1 knockout...

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Publicat a:Mol Psychiatry
Autors principals: Segev, Amir, Yanagi, Masaya, Scott, Daniel, Southcott, Sarah A., Lister, Jacob M., Tan, Chunfeng, Li, Wei, Birnbaum, Shari G., Kourrich, Saïd, Tamminga, Carol A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344327/
https://ncbi.nlm.nih.gov/pubmed/30038231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0124-3
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